Research Associate / Senior Research Associate, In Vitro Biology
Type: Full Time
Required Education: 4 Year Degree
Academic / Research
Life Science & Biopharmaceutical Companies
Internal Number: 001
We are seeking a highly motivated and collaborative Research Associate or Senior Research Associate to join our in vitro Biology team at Crinetics. The successful candidate will be an integral member of multidisciplinary teams working on unmet needs in endocrine related diseases and striving to make a real difference in the lives of patients. Their primary role will be providing in vitro pharmacology data that supports lead optimization campaigns, mechanism of action studies, and new target efforts in an environment that values scientific integrity and quality, and fosters learning, open communication, collaboration, and teamwork.
ESSENTIAL FUNCTIONS AND RESPONSIBILITIES:
Design, develop, optimize, validate, execute, troubleshoot, and analyze in vitro pharmacology assays under minimal supervision to generate high quality, reproducible data. Assays include, but are not limited to, biochemical, cell-based functional, and radioligand binding.
Critically analyze and insightfully interpret data
Efficiently and accurately document protocols and results in an electronic laboratory notebook
Maintain multiple cell lines in culture
Regularly present clear written and verbal data summaries
Maintain familiarity with current scientific literature and pertinent new technologies. Adapt concepts from literature to bench research to support ongoing studies.
Other duties as assigned
EDUCATION, EXPERIENCE, KNOWLEDGE, SKILLS AND ABILITIES:
BS and a minimum of 3 years of experience in an in vitro biology lab including biochemical, cell-based functional, and radioligand binding assays
Practical experience with a broad range of in vitro biological assays (especially assays investigating GPCRs)
Experience culturing cells with sterile (aseptic) technique
Outstanding experimental design, problem-solving, and data analysis skills
Ability to rapidly learn new assays and process data
Ability to effectively multitask and advance various projects simultaneously without compromising data quality or reproducibility
Ability to work independently as well as in a team environment toward timely execution of shared team deliverables
Enthusiasm for developing an expanding technical and theoretical knowledge base
Excellent communication (written and verbal), time management, organizational and interpersonal skills to ensure operational excellence of daily laboratory needs
TECHNICAL KNOWLEDGE REQUIRED:
Equipment: PC, e-mail systems, and common office machines, or ability to be trained. Knowledge of other equipment required: Familiarity with biology lab equipment (pipets, pH meter, centrifuges, liquid handlers, microplate readers, etc)
Software Knowledge: Windows, MS Office (Outlook, Word, Excel, PowerPoint). Knowledge of other software required: GraphPad Prism experience is an asset.