The Data Scientist, Bioinformatics will be a key member of the Core Technology team and will develop and implement software tools and algorithms focusing on Next Generation Sequencing (NGS) data to advance ARCUS nuclease development and improve genome editing outcome analysis.
The Data Scientist will work closely with Genomics team members to improve and polish current in-house software and translate scripts into software for general scientific consumption. The individual will also leverage current literature to propose and implement new data analysis pipelines that complement and advance the current system of genomic analysis as well as run current analysis pipelines as needed.
The ideal candidate will have extensive experience and knowledge in NGS data analysis. They will have a proven track record of software development for data analytics or bioinformatics applications. The candidate must have a high level of independence to carry out their responsibilities with minimal supervision.
Essential Dutiesand Responsibilities
Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of this position.This list contains the major duties and requirements of the job and is not all-inclusive. Incumbent(s) may be expected to perform role-related duties other than those contained in this document.
Leverage advanced computation approaches and collaborate with Genomics team members to create advanced assays for genome editing outcomes
Analyze experimental data produced by next-generation sequencing (NGS) including RNAseq and indel analysis
Maintain current and develop new computational and bioinformatic tools
Develop visualization tools for large scale genomic projects
Perform additional duties and responsibilities, as assigned
The requirements listed below are representative of the knowledge, skill, and/or ability required to perform this job successfully.
PhD in Computational Biology, Bioinformatics or related field or Master’s degree and 2+ years of experience in Computational Biology, Bioinformatics or related fields, or equivalent combination of training and experience
Proficiency using Python for data analysis
Proficient in NGS data processing in a Linux computing environment
Some experience in R, shell scripting
Foundation in basic genomics concepts
Familiarity with publicly available bioinformatics databases, tools, algorithms, and websites, such as NCBI, UCSC, ENSEMBL, ENCODE, 1000 Genomes or NHGRI
Experience using visualization tools (ggplot2, seaborne, etc.)
Basic understanding of statistics and algorithms associated with genomics analysis
Experience working independently and within a team depending on project needs
Strong communications skills
Software engineering experience with Python
Experience in multiple NGS assays such as RNAseq, bisulfite sequencing, or single cell analysis
Versioning software (git, etc.)
Experience using Rmarkdown or Jupyter notebooks
Experience with SQL databases
Internal Number: PBI-CT-001
About Precision BioSciences
Precision BioSciences, Inc. (Nasdaq: DTIL), is a clinical stage biotechnology company dedicated to improving life (DTIL) with its novel and proprietary ARCUS® genome editing platform. This isn’t just a statement supporting the products that we’re developing – it’s a statement that speaks to our collective desire to do our part in improving the lives of those around us. ARCUS is a highly specific and versatile genome editing platform designed with therapeutic safety, delivery, and control in mind. Using ARCUS, Precision is developing allogeneic CAR T and in vivo gene correction therapies for cancer and genetic diseases. Our team includes pioneers in genome editing, leaders in business, and a full staff of talented and committed people who are excited to be a part of medical and scientific breakthroughs. For additional information, please visit www. precisionbiosciences.com
Precision BioSciences actively fosters an inclusive environment to ensure we attract and retain the best talent; we value diversity of life experiences and perspectives; and we encourage innovation in pursuit of our mission. We provide equal employment opportunities (EEO) to all employees and applicants for e...mployment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, disability, genetic information, marital status, amnesty, or status as a covered veteran in accordance with applicable federal, state and local laws. Precision BioSciences complies with applicable state and local laws governing non-discrimination in employment in every location in which the company has facilities. This policy applies to all terms and conditions of employment, including, but not limited to, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.