Department: MED-Center for Genetic Med
Salary/Grade: NEX/9

Job Summary:

We are seeking a full-time research technician to conduct defined experiments.  Qualified candidates will be detail-orientated, reliable, demonstrate solid written and verbal skills, and have the capacity to learn new techniques.  The lab studies genetic mechanisms contributing to the development of inherited human diseases, with a focus on cardiac and muscle disease.  By combining gene discovery with the use of model systems, we aim to better understand disease biology and evaluate the potential of new therapeutics.  A candidate interested in translational science with a background in biological sciences and previous wet lab experience is preferred

The Research Technologist 1 conducts tests and procedures; sets up and operates equipment; records observations and measurements and collects and compiles data in a research lab; requires a practical understanding of a limited number of standard scientific techniques.

Specific Responsibilities:

• Follows pre-defined protocols, policies, procedure, regulations, Good Clinical and Good Laboratory Practices and conducts standard and repetitive experiments and completes basic trouble-shooting techniques.
• Sets-up, operates and maintains standard lab equipment.
• Using an entry level of skill, completes the following activities:

Molecular Biology:

• DNA, RNA, Protein isolation, purification and expression 
• Western blotting
• PCR, RT-PCR
• Plasmid preparation
• Cloning, mapping and sequencing of DNA
• Recombinant virus production and purification

Cellular Biology:

• Cell culture, cell isolation
• Functional studies
• Transfection

Histology:

• Tissue fixation/processing: embedding, preparation of blocks and sectioning, staining
• Immunohistochemistry
• Microscopy

Immunology:

• Flow cytometry
• Cytokine assay
• Antibody production and purification

Animal:

• Husbandry
• Breeding and screening transgenic mice
• Dissections
• Blood collection
• Surgical procedures
• Database management of colony

• Records test results and may maintain databases.  
• Completes standard and routine clerical duties such as copying, filing, data entry, word processing, etc. 
• Maintains inventory of reagents, mice and lab supplies
• Performs other duties as assigned.

Minimum Qualifications:

• HS diploma or equivalent and some basic science courses is required.

Minimum Competencies: (Skills, knowledge, and abilities.)

• Demonstrated laboratory experience;
• Demonstrated ability to follow detailed instructions as required by research protocols;
• Demonstrated computer skills, including spreadsheets and basic computations;
• Attention to detail and accurate record keeping;
• Ability to work independently and in a team environment;
• Manual dexterity.

Preferred Qualifications:

• Successful completion of a full 4-year course of study in an accredited college or university leading to a bachelor's or higher degree in a scientific major.
• Preferred candidates will have previous experience in a molecular and/or cell biology research lab.

Preferred Competencies: (Skills, knowledge, and abilities)

• Knowledge of basic molecular biology techniques
• Cell culture, microscopy, and /or animal model handling experience
• Highly organized and has the ability to multi-task
• Capable of learning new techniques

Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women, racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply. Hiring is contingent upon eligibility to work in the United States.