Our lab studies how early life stress changes brain development and ultimately increases risk for depression and other psychiatric diseases. We are specifically interested in how stress in developmental sensitive periods alters transcription and transcriptional regulation across the genome and across development, to increase sensitivity to future stress. We are using a mouse model of stress across the lifespan and a variety of sequencing and bioinformatic approaches. This is a full-time position for a postdoc or more senior researcher with advanced bioinformatic training. The position will focus primarily on bioinformatic analysis of existing (bulk RNA-seq, sorted ATAC-seq) and forthcoming (snRNA-seq, snATAC-seq, sorted ChIP-seq/similar) datasets, but will have the opportunity to lead their own project directions, including generating or collaborating to generate new datasets themselves, with training as needed. Thus far, trainees in the lab have been working on the complete pipeline from mice to molecular approaches to bioinformatic analyses and back, which means that we all do at least some analysis ourselves, but also that this position should be able to multitask several projects simultaneously. The lab is highly collaborative, but also structured so that every full-time person has at least one project where they are the clear lead and 1st author; it will be the same for this position. This is a one year term position with the possibility of renewal pending satisfactory performance and funding. Applicants should have experience performing a variety of bioinformatic analyses, have an interest in translational neuroscience, and be collaborative. Experience with single cell pipelines (Cell Ranger / Seurat) and pseudotime analyses will be prioritized. Applicants should be extremely organized, have high attention to detail, and be able to work independently. Any candidate who can make a case for their background and/or envisioned research contributing to the lab's research program will be given full consideration and is strongly encouraged to apply.Applications from members of groups historically under-represented in neuroscience are encouraged.Interested applicants must apply through https://www.princeton.edu/acad-positions/position/19342 and include a cover letter stating background and professional interests, a CV including publications, and contact information for two or more referees. Review of applications will continue until the position is filled.
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