Project Scientist position in cancer biology is available immediately in the Boiko lab at the Department of Medicine, Samuel Oschin Cancer Center, Cedars-Sinai Medical Center. The Candidate will participate in the NIH funded projects investigating strategies to target critical signaling pathways and immune checkpoints in melanoma and other solid tumors. These projects will entail molecular biology approaches including cloning, shRNA and CRISPR techniques, in-vitro proliferation and activation assays of human tumor cells and the immune cell lineages (including but not limited to Macrophages and T-Cells). These studies will also involve genetic and patient derived xenografted tumor models in mice, including in-vivo testing of the candidate therapeutic agents.
Applicants who possess solid experience and demonstrated robust productivity in the areas listed above are especially encouraged to apply.
A separate group of projects will involve system biology approaches to generate and analyze gene expression and sequencing data at the tissue and single cell level to unravel molecular evolution of tumor progression and identify novel critical gene targets. Candidates with solid bioinformatics background are encouraged to apply for these projects.
Successful applicants will have excellent publication record, strong self-motivation and passion for scientific discovery and be able to work effectively as a team member. Submit application materials online and email the copy of your resume to Alexander.Boiko@cshs.org
The Project Scientist works independently and in cooperation with the Principal Investigator to make significant and creative contributions to a research or creative project in any academic discipline. The Project Scientist may be an ongoing member of a research team or may be employed for a limited period of time to contribute high-level skills to a specific research or creative program.
Project Scientists are not required to carry out independent research or to develop an independent research reputation and do not have teaching responsibilities. Ordinarily, the Project Scientist title will carry out research or creative programs as well as administration of day-to-day lab operations with supervision by a member of the Professorial Series.
In addition the Project Scientist will be responsible for the following:
May assist in preparation of grant proposals, submissions, publications and presentations but is not responsible for generating grant funds.
May serve as PI for certain grants as approved by supervising member of the Professorial Series.
May participate in publications and presentations as author or co-author.
May develop, adapt and implement new research techniques and protocols.
Assists in lab experiments.
Analyzes, interprets, summarizes and compiles data.
May lead or train Staff Research Associates and Research Fellows.
Will assist in day-to-day laboratory activities.
Appointees on an academic trajectory will be expected to commit a portion of their time to developing an independent range or research.
PHD or Highest Degree in the field is required.
Completion of postdoctoral appointment in area of specialization, as applicable
Knowledge of PI's area of research specialization
Demonstrated technical competency in a variety of research techniques and protocols.
Experience with pathology analysis of human tissues
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major t...eaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.