Our Postdoctoral Scientist will focus on studying the role of microglia in Alzheimer's Disease pathogenesis and evaluating molecules that can augment microglial function and neurotoxic Amyloid-beta (A b ) processing and homeostasis in the brain. Our successful candidate will hold a Doctoral Degree (preferably with expertise in microglia biology and Alzheimer's disease, but at a minimum with neuroscience, neurobiology, molecular biology or a closely related field). You must have experience with translational research using animal models to study mechanisms of gene function and disease pathogenesis. Experience in molecular biology, cell culture, immunocytochemistry, Western blotting, PCR, quantitative real-time PCR and histology/imaging techniques including quantitative bright-field and fluorescence microscopy and confocal microscopy is required. Experience with proteomics analysis of isolated protein complexes will be beneficial for some of the planned protein-protein interaction experiments.
You will be expected to collaboratively design experiments, and independently collect and analyze data, troubleshoot experimental protocols, consolidate data for publication and grant applications, present research at national and international meetings, and prepare manuscripts for publication. Teaching and supervising other research staff, students, and residents may be required.
As a Postdoctoral Fellow, you will work independently and in cooperation with the Principal Investigator to make significant and creative contributions to the assigned research project. R esearch projects assigned are developed under the direction and in collaboration with the Principal Investigator, Warren Tourtellotte, MD, PhD, Professor and Vice-Chair of Pathology and Laboratory Medicine and Professor of Neurology, Neurosurgery and Biomedical Sciences. You are expected to have substantial scientific independence, organization, creativity and motivation. A significant track-record of scholarly productivity and strong evidence of successful predoctoral experimental design and execution is expected and essential.
In addition to professional development opportunities, Cedars-Sinai offers competitive compensation and benefits package: Medical, Dental, 403(b) with match in addition to Cedars-Sinai's paid Retirement Program, Tuition Assistance, Credit Union, Wellbeing Program Rideshare, Employee Discounts, Healthcare and Dependent Care Reimbursement Accounts, Group Life/AD&D and Long Term Disability Insurance, start at 16 vacation days/year.
Cedars-Sinai is an Equal Opportunity Employer that welcomes and encourages diversity in the workplace. EEO /AA/F/M/Veteran/Disabled.
PhD or highest Degree in their field is required
Demonstrated significant, original, and creative contributions to a research or creative program or project.
Knowledge of PI's area of research specialization.
Demonstrated technical competency in a variety of research techniques and protocols.
The position requires working with microscopes, computers and at the lab bench for extended periods of time, and it requires the use of specialized laboratory equipment.
Must be able to sit, stand and/or stoop for long periods of time.
Must be able to lift at least 20 pounds.
Working Title: Postdoctoral Scientist - Department of Pathology/Alzheimer's Disease Pathogenesis - Tourtellotte Lab
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major t...eaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.