Research Associate II-Biochemistry, Cellular and Molecular Biology Regular Full-time A research associate position is available immediately to study programmed DNA elimination in multiple cellular organisms. The research will be conducted in the Wang lab (https://dnaelimination.utk.edu/) that is located in the Ken and Blaire Mossman Building on the campus of the University of Tennessee, Knoxville. Programmed DNA elimination is a developmental process in which portions of the genome are reproducibly eliminated. This process occurs in the single-cell ciliates as well as in diverse eukaryotes. During DNA elimination in nematodes, the chromosomes break, some chromosome fragments are lost, and new chromosomes are formed. Areas under investigation in the lab include 1) how break regions are identified and how the breaks are generated, 2) how broken DNA ends are repaired during DNA elimination, and 3) the contributions of epigenetic factors including histone modifications, 3D genome organization, and non-coding RNAs to DNA elimination. Duties/Responsibilities: Candidate is expected to design and carry out independent research, write grant applications (if applicable), and publish papers. Candidate must be self-motivated, has a strong aptitude for research, and the ability to quickly learn new areas of research and carry out experiments in a new system. The candidate's primary responsibility will be to conduct research. Good organizational and computer skills and the ability to work independently as well as part of a team are necessary.
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