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The Gale Lab in the UW Department of Immunology has an excellent opportunity for a Research Scientist 3 to focus on COVID-19 virology research.
The Research Scientist 3 will, under general guidance from the principal investigator, perform virologic research, including virus isolation and viral growth analysis from primary clinical specimen in a biosafety level 3 (BLS3) laboratory. This work will be focused on isolating SARS-CoV-2 from specimen, examining virus growth under conditions of antiviral drug treatment in cultured cells, and conducting molecular virology analyses including running next generation RNA sequencing of the SARS-CoV-2 genome to identify drug-resistant viral genome sequences. The position will include computational analyses of viral genome sequences and use of molecular biology and molecular virology applications to assess the viral phenotype of specific viral genome mutations.
RESPONSIBILITIES •Optimize and perform complex immunologic and viral drug resistance assays in vitro tissue culture systems infected with SARS-CoV-2. •Produce virus stocks and conduct quality assurance analysis of each stock. •Develop extensions of existing methods and protocols. •Work independently with the ability to design insightful experiments. •Provide status reports to the project manager, research assistant professor, and/or principal investigator. •Perform molecular biology techniques including PCR analysis, western blotting, qRT-PCR, and cDNA cloning. •Performs next-generation sequencing protocols to define viral genome sequence. •Organize and record data; detailed and meticulous record keeping is required. •Participate actively in laboratory meetings. •Assist other laboratory members with BL3 experiments. •Perform data analysis and assist in the quality control of data. •Participate in laboratory meetings. •Perform related duties as required.
MINIMUM REQUIREMENTS •Doctoral degree in biological sciences or related field with two or more years or relevant experience.
Additional Requirements: •Must be able to work independently and have strong attention to detail. •Ability to work in a team and collaborative environment; experience working on collaborative projects to design and implement studies. •Must be highly motivated with excellent time management skills. Willingness to quickly change direction and priorities based on a rapidly evolving research program. •Ability to organize and maintain accurate records. •Experience using Excel, PowerPoint, and other common Microsoft Office/365 software.
Equivalent education and/or experience may substitute for minimum requirements.
DESIRED REQUIREMENTS •Laboratory experience in a similar virology research setting.
CONDITIONS OF EMPLOYMENT •The individual in this position will be working with SARS-CoV-2; it is the employee's personal responsibility to follow all UW Environmental Health & Safety and BSL 3 safety protocols and procedures. •Ability to work in a laboratory setting. •Ability to work flexible hours to meet experimental and project deadline requirements.
Application Process: The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
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