The Menon Lab, in the Department of Neurology at Columbia University Medical Center, is seeking a part-time Short-Term Casual to continue working on an ongoing spatial transcriptomics project investigation cell type composition in the human cortex. This project is part of an ongoing effort to characterize changes in cell type composition and spatial arrangement in response to pathology associated with Alzheimer's and other neurodegenerative diseases.
Develop models to deconvolve spot-level data in spatial transcriptomics arrays
Generate presentation and publication level figures as needed
Develop a general code base to disseminate the software tools that result from this analysis, since these tools will be widely applicable to the field.
High School Diploma.
Prior experience analyzing single-nucleus RNA-seq and spatial transcriptomics data on post-mortem human brain tissue.
Familiarity with neuroscience, in particular Alzheimer's Disease pathology and disease progression.
Proficiency in R programming, especially with the keras package for machine learning.
Familiarity with standard computational genomics algorithms.
Knowledge of commonly used statistical tests and regression models for differential gene expression.
Equal Opportunity Employer / Disability / Veteran
Columbia University is committed to the hiring of qualified local residents.
Internal Number: 510545
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