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The Division of Allergy and Infectious Diseases in the Department of Medicine has an outstanding opportunity for a full-time Research Scientist/Engineer - Assistant.
Under direct supervision, this Research Scientist-Assistant will perform laboratory research work in support of studies on drug discovery. The overall goal of the research is to find new drugs for the treatment of infectious diseases. Work will be done in collaboration with the UW Biochemistry and Chemistry Departments who will supply the novel compounds to test for inhibition of parasitic enzymes.
Additional Background: Team member of the UW Ojo laboratory located at the South Lake Union campus involved in new drug discovery against neglected diseases, ie malaria and giardiosis, etc. Research compounds are screened for both humans and veterinary implications. Funding is provided by various NIAID grants
Duties & Responsibilities:
Maintain daily tissue cultures and perform cytotoxicity assays on mammalian cell lines
Test research compounds for activity against organisms in both in vitro and animal models
Development and performance of kinetic enzymatic assays. Using proteins produced within the lab to enzymatic test research compounds for effectiveness
Perform in vitro assays of possible drug compounds
Data analysis and preparation of reports (detailed notebook)
Prepare reagents to perform experiments
As a UW employee, you will enjoy generous benefits and work/life programs. For detailed information on Benefits for this position, click here.
Bachelor's degree in Biology, Biochemistry, Microbiology, or related field and at least 3 months experience. Experience can substitute for degree requirement.
Molecular biology techniques such as DNA isolation/manipulation, PCR, sequencing, electrophoresis.
Good sterile technique and and the ability to perform tissue culture techniques and maintain cultures.
Willingness and experience working with animal models (mouse).
Experience in analytical chemistry, mass spectrometry and other biophysical characterization techniques.
Ability to prepare reagents, manage data and keep a detailed notebook.
A high level of motivation, good organizational skills and the ability to work as a member of a team.
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
Previous work with malaria and animal studies. Knowledge of LC-MS analysis
Familiarity with database and graphing software.
Previous work with micro organisms and animal studies. Knowledge of LC-MS analysis
CONDITIONS OF EMPLOYMENT
Application Process: The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Workforce Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
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