A postdoctoral scholar is to be hired to carry out studies linked to the goals and objectives of NIH AG069819-01. Specifically, a position is available to analyze the effect of oxidized lipids, specifically 4-hydroxynonenal (4HNE) on acquisition of the senescence phenotype by preadipocytes. Experience with signal transduction pathways linked to Wnt signaling and DNA repair will be profiled and the covalent modification of cellular proteins by 4HNE will be evaluated.
25% Mass Spectrometry based analysis and quantitation of 4HNE
50% Evaluation of Wnt signaling by 4HNE, acquisition of the senescent phenotype. Analysis of DNA repair pathways induced by 4HNE
25% Preparation and submission of grants and manuscripts
Required Qualifications: Minimum required qualifications include PhD in biochemistry or related discipline.
Preferred Qualifications: Experience with lipid metabolism and mass spectrometry. Evaluation of oxidized lipids and signal transduction.
Internal Number: 337964
About University of Minnesota, Twin Cities
The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.