Lab of Klaas van Wijk, Section of Plant Biology, School of Integrative Plant Sciences (SIPS), Cornell University, Ithaca, NY, USA
The van Wijk lab has a 20+ history in plant proteomics and mass spectrometry to study biological questions in Arabidopsis and other plants species. The van Wijk lab has an in-house mass spectrometer (QExactive), an extensive bioinformatics proteomics processing ‘pipe-line’ and houses the Plant Proteome Data Base (PPDB). Together with colleagues in the Systems Biology Institute (ISB) in Seattle we are also funded by the National Science Foundation to build an Arabidopsis PeptideAtlas by reprocessing millions of publicly available mass spectrometry data. The postdoc will be part of a team to study chloroplast proteolysis in Arabidopsis thaliana, including protease substrate selection mechanisms, protease structure-function analysis, and quantitative proteomics of single and higher order chloroplast protease mutants. The Postdoc will also contribute to truly large-scale plant proteomics & mass spectrometry data analysis in collaboration with the ISB. The van Wijk lab is funded through awards from the National Science Foundation. This postdoc position provides an excellent training opportunity in plant protein biochemistry and mass spectrometry, chloroplast proteostasis, plant systems biology and bioinformatics.
Recent publications from the van Wijk Lab: Bhuiyan et al (2020) Auto-catalytic processing and substrate specificity of Arabidopsis chloroplast glutamyl peptidase. Plant Physiology; Montandon et al (2019) In vivo trapping of candidate protease substrates and adaptors of the chloroplast CLPC1 chaperone. Journal Proteome Research; Liao & van Wijk (2019) Discovery of AAA+ protease substrates through trapping approaches. Trends in Biochemical Sciences; Majsec et al (2017) The Plastid and Mitochondrial Peptidase Network in Arabidopsis thaliana: A Foundation for Testing Genetic Interactions and Functions in Organellar Proteostasis. The Plant Cell; Bhuiyan et al (2016) Plastoglobule localized metallopeptidase PGM48 is a positive regulator of senescence in Arabidopsis thaliana. The Plant Cell; Lohscheider et al (2016) Phosphorylation of plastoglobular proteins in Arabidopsis thaliana. J. Exp Botany; Rowland et al (2015) The Arabidopsis Chloroplast stromal N-terminome; complexities of N-terminal protein maturation and stability. Plant Physiology; Friso & van Wijk (2015) Update: Post-translational protein modifications in Plant Metabolism. Plant Physiology
Qualifications: The applicant must have a PhD degree and a strong background in large scale proteomics and mass spectrometry (ESI-MSMS), as is evidenced by several publications in International Journals. Training in Plant Biology would be highly beneficial.
Application Instructions: Submit a letter summarizing your background and qualifications, a statement of research accomplishments and interests (3 pages maximum), a detailed curriculum vitae, and the names of three references by email to firstname.lastname@example.org. Klaas J. van Wijk, Professor and Chair, Section of Plant Biology, School of Integrative Plant Sciences (SIPS), Cornell University, Ithaca, NY 14853, USA. For more about the van Wijk lab http://blogs.cornell.edu/vanwijk/. Review of applications will begin immediately and will continue until the position is filled.
Internal Number: august-2020-1
About Cornell University
Cornell University is an Ivy league research University in Ithaca, NY, USA