Essential Functions: Perform organic synthesis, purification, characterization and quality control of radiopharmaceutical precursors.Perform and optimize radiosynthesis, small animal imaging, distribution and data analysis. Conduct external validation of radiotracer binding and uptake via molecular biology assays.Perform oncology and CNS animal model development and monitor animal health periodically.Implement radiation safety protocols established by the lab. Maintain an up-to-date lab notebook, documentation and other record-keeping activities as necessary.Prepare and assist in manuscript and grant writing, publish and present research findings at annual domestic/international conferences. Other duties as assigned.
Qualifications: PhD in chemistry, biochemistry, organic/medicinal chemistry required.Experience or willingness to learn fluorine-18 and radiometals chemistry, in vivo animal work, imaging, bioconjugate chemistry, antibody engineering and data analysis.Proficient or willing to learn in vivo animal handling and manipulation. Knowledgeable in the following techniques: HPLC, NMR, MS, flow cytometry, western blots, immunohistochemistry, cell culture.Independent, can work with minimal supervision, organized, motivated to learn and drive the research to completion.
Internal Number: 76_208141
About Wayne State University
Founded in 1868, Wayne State University is a nationally recognized metropolitan research institution offering more than 400 academic programs through 13 schools and colleges to nearly 32,000 students. Wayne State?s main campus in Midtown Detroit comprises 100 buildings over nearly 200 acres; its five extension centers offer higher education to people throughout Southeast Michigan. Wayne State is dedicated to preparing students to excel by combining the academic excellence of a major research university with the practical experience of an institution that by its history, location and diversity represents a microcosm of the world we live in. Reflecting its location and the excellent international reputation of its graduate schools, particularly in the sciences, Wayne State boasts the most diverse student body among Michigan?s public universities. Its students represent 49 U.S. states and more than 60 countries.