As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem solving skills and dedication to build stronger minds and a healthier world.
UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty. All of which has allowed the UW to be nationally recognized as a “Great College to Work For” for six consecutive years.
The Division of Metabolism, Endocrinology, and Nutrition in the Department of Medicine has an outstanding opportunity for a full-time Research Scientist/Engineer 2.
The overall purpose of the University of Washington Diabetes Research Center (DRC) is to enhance diabetes-related research of Affiliate Investigators at the University and other institutions in the greater Seattle area. The Center is comprised of five biomedical cores which provide services to the DRC Affiliate Investigators.
The Diabetes Research Center (DRC) Cell Function Analysis Core is a broad-based resource for research involving pancreatic islets and other tissue important to the development of diabetes and its complications. Services include preparing isolated islets and other tissue from rodents, and experimental analysis tissue with respect to their metabolic, functional and morphological state. Flow culture devices combined with sophisticated real time cellular assessment techniques using optical detection have been developed and provide a unique set of investigational tools. Classes of studies carried out have involved control of insulin secretion, beta cell death, mitochondrial metabolism, stimulation secretion coupling, drug development, development of instrumentation, phenotyping genetically altered mice and binding studies.
Major responsibilities and Duties:
Activities center on performing procedures and generating data that support scientific investigation, publications and grant funding applications by researchers focused on diabetes.
This position is in the Cell Function Analysis Core of the Diabetes Research Center and involves isolation of islets and other cell types using microsurgical and gradient purification techniques and cell culture; and comparing the function, bioenergetics and intracellular signaling in cells from normal and diabetic models or patients using a variety of assays. In addition, effort will be on the development of instrumentation for cell analysis that involves the design, implementation, testing and optimization of optical sensors and microfluidics.
Specific Duties and Responsibilities:
Isolation of pancreatic islets and tissue from rodents using microsurgical and gradient purification techniques.
Culture of islets, tissue and cell lines.
Assess metabolic and functional viability of tissue/cells using sophisticated, real-time spectroscopic and imaging techniques.
Perform biochemical assays using fluorometric, spectrophotometric and liquid scintillation techniques.
Test modifications of research protocols, methodology and laboratory equipment.
Analyze and report experimental results during laboratory meetings and in writing.
Keep careful and accurate laboratory records.
Maintain laboratory equipment.
Order supplies as needed.
Compliance with regulation of drugs, radioactivity and animal usage.
As a UW employee, you will enjoy generous benefits and work/life programs. For detailed information on Benefits for this position, click here.
Bachelor’s degree or higher in an appropriate field and two to four years experience in a related area or equivalent.
Experience in a related area, and experience in rodent microsurgery and islet techniques.
Must have experience with cell and primary tissue culture and general experience with life sciences laboratory techniques.
Must be willing to work with rodents and be flexible with work schedule during long experiments.
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
Ability to test and optimize analytical tools used in our laboratory and modify them for application to a wide variety of tissues and questions being addressed; penchant and aptitude for engineering and design.
CONDITIONS OF EMPLOYMENT
Application Process: The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Workforce Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
Founded in 1861, the University of Washington is one of the oldest public institutions in the west coast and one of the preeminent research universities in the world. The University of Washington is a multi-campus university comprised of three different campuses: Seattle, Tacoma, and Bothell. The Seattle campus is made up of sixteen schools and colleges that serve students ranging from an undergraduate level to a doctoral level. The university is home to world-class libraries, arts, music, drama, and sports, as well as the highest quality medical care in Washington State and a world-class academic medical center. The teaching and research of the University’s many professional schools provide undergraduate and graduate students the education necessary toward achieving an excellence that will serve the state, the region, and the nation. As part of a large and diverse community, the University of Washington serves more students than any other institution in the Northwest.