The Research Assistant will work with a team of researchers for the Taub Institute for Research on Alzheimer's Disease and the Aging Brain. The nature of the research is understanding cellular and molecular mechanisms of Alzheimer's disease, cognitive aging, and related disorders. He/she will also contribute conceptual as well as interpretive assistance to the development and implementation of novel ideas that involve possible therapeutic approaches to drug discovery for Alzheimer's disease. Perform other related duties as assigned.
Conducting various wet lab experiments including but not limited to Tissue processing, Western blotting, PCR and DNA gel electrophoresis, ELISA, RNA FISH, and Fluorescent immunohistochemistry.
Maintaining animal colonies (primarily mice), genotyping and breeding animals to produce mice of high quality, including care and feeding, cleaning of the equipment and physical surroundings, and constant concern for the health of each animal.
Learning new protocols and experimental techniques to conduct and implement novel experiments in the lab.
Requires a Bachelor's Degree and at least 1.5 years of related experience or equivalent in education, training and experience.
Master's degree in biomedical sciences.
Candidate must have an understanding of the anatomy of mouse brain as well as experience working and maintaining a fully functional wet lab, including proficiency in the biochemistry techniques of Western Blotting, PCR and gel electrophoresis, ELISA, and immunohistochemistry, including relevant analytical techniques.
Experience in Alzheimer's disease research.
Experience with mouse husbandry in addition to perfusion, dissecting and slicing sections of the mouse brain using a cryostat.
Proficient in cell culture techniques for primary cell lines and immortalized cells. Experience working with BSL2 biosafety cabinet.
Proficient in data recording/analysis in statistical/spreadsheet formats (MS Excel, MS Word, Powerpoint).
Candidate is expected to pay close attention to even minor details while conducting experiments.
Equal Opportunity Employer / Disability / Veteran
Columbia University is committed to the hiring of qualified local residents.
Internal Number: 506609
About Columbia University
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.