A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.
Please apply with your cover letter and CV to this posting: ID 184195
Among other projects, the goal of our projects is to enhance success rate of drug development in clinical trials by developing methods to optimize compounds for improving efficacy and tissue targeting in relevant disease (Various cancers, Myelofibrosis, Rheumatoid Arthrisis, Ulcerative Colitis).A postdoctoral researcher position in medicinal chemistry is available for a highly motivated individual interested in Activity-DMPK driven structure optimization of small molecules. This position is within a multi-disciplinary and highly collaborative research group. The successful applicant should have a strong background in organic/medicinal chemistry but also show interest in other areas of research relevant to the lab (or to the project) such as, biology and pharmacokinetics.
The successful candidate will independently perform the following routine studies and research studies:
Create hypotheses, design compounds, and carry out multi-step synthesis of small molecules
Analyze complex data sets to generate hypotheses for structure and properties optimization
Regular report of research progress in group meeting and active participation in discussion
Work well independently and as a member of a highly collaborative team
PhD (or equivalent degree) in Organic/ Medicinal Chemistry
Strong ability to implement synthetic/medicinal chemistry design strategies to address compound liabilities
Solid mechanistic understanding to perform troubleshooting
Experience in molecular modeling or ligand/protein structure visualization to propose hypotheses for optimization (desired but not required)
The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks. Background checks are performed in compliance with the Fair Credit Reporting Act.
The University of Michigan is an equal opportunity/affirmative action employer.
Internal Number: 184195
About University of Michigan - Ann Arbor
A great university is made so by its faculty and staff, and Michigan is recognized as one of the best universities to work for in the country. The Michigan culture is known for engaging faculty and staff in all facets of the university to create a workplace that is vibrant and stimulating.For two consecutive years, the Chronicle of Higher Education has placed U-M in its "Great Colleges to Work For" survey. In particular, the university earns high marks for strong relations between faculty and administrators, a collaborative system of governance, strong pay and benefits, and a healthy work/life balance.