The research associate will be expected to develop a research project that is focused on understanding the molecular basis of selective neuronal vulnerability in Alzheimer’s disease (AD) and related dementias, with an eye on how this knowledge might contribute to therapy. Newly funded projects include 1) human tissue-based studies of tau dysregulation and pathology in mild cognitive impairment (MCI) and AD, and 2) human tissue and in vivo rodent-based studies of vascular contributions to MCI and AD. The projects involve expertise in general molecular, biochemical, histological, and microscopy techniques, as well as advanced functional genomic methodologies and in vivo techniques in animal models. Duties will include helping in the day-to-day operations of the lab, collaborative experimental design, conducting independent research, data analysis, presenting data at conferences, and writing manuscripts for publication in peer-reviewed journals. The applicant will also gain exposure in mentoring graduate students and have the opportunity to explore career options. This position is in Grand Rapids, MI.
Doctorate -Neuroscience, Neurodegeneration
The position requires a doctoral degree in a biomedical research discipline which included at least 4 years of experience in a research laboratory.
Individual should be familiar with common biological laboratory research techniques and have a basic understanding of biochemistry, molecular biology, cell biology and physiology.
Applicants should be able to demonstrate his or her experience with conducting research studies independently, fundamental statistical analysis, and the preparation of results for publication as a scientific manuscript.
At least one first author paper in a peer-reviewed journal is expected.
Good command of spoken and written English is a requirement.
Training in the discipline of neuroscience with a focus on brain diseases and/or research experience in the field of Alzheimer's disease and related dementias is highly desired.
Experience with some or all of the following techniques is also desired: advanced molecular biology and biochemical techniques such as cloning, gene regulation and protein analysis; cell culture modeling and analysis; rodent husbandry, surgical procedures, behavioral analysis, and necropsy; human and rodent tissue processing, immunohistochemistry, and microscopic analysis; stereologic procedures; RNA sequencing and/or proteomics; and statistical analysis including familiarity with R or similar statistical computing programs.
Highly competitive applicants will have multiple authorships including at least one first-author manuscript in a peer-reviewed journal.
Required Application Materials
Curriculum Vitae, Names of 3 references, 1-2 page statement highlighting past accomplishments and future goals.
Review of Applications Begins On
Summary of Health Risks
Work with animals or unfixed animal tissue.
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Internal Number: 634296
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