Calico is a research and development company whose mission is to harness advanced technologies to increase our understanding of the biology that controls lifespan and health span, and to devise therapeutic interventions that enable people to lead longer and healthier lives. Executing on this mission will require an unprecedented level of interdisciplinary effort and a long-term focus for which funding is already in place.
Calico is seeking a scientific software developer with experience in mass spectrometry and proteomics, in order to build data processing pipelines for high-throughput and/or high-content data. As a member of the Computing team, you will work closely with a talented cross-functional team of data scientists, software engineers, automation engineers, and bench scientists.
Develop and maintain software pipelines for the processing, visualization, and analysis of proteomics mass spectrometry data
Integrate pipeline with algorithms developed in-house, and with public & private/licensed software modules
Understand the details of proteomics experimental workflows, data representations, as well as analysis algorithms; stay abreast of current state of the art in mass spec informatics
Work closely with software architect, data engineer(s) and data wranglers, proteomics data scientists, project manager, UX designer, and mass spec lab lead to translate scientific needs into scalable, readable, maintainable code
Regularly communicate work in written and verbal presentations
Degree in quantitative discipline such as computer science, mathematics, computational biology, or bioinformatics
2+ years’ experience working as a software developer in a scientific organization (national lab, biotech, pharma)
Outstanding communication and interpersonal skills
Fluency coding in a Unix/Linux environment in Python, C/C++, or Java
Substantial programming experience, i.e. having written or maintained codebase using software best practices (e.g. unit tests, self-documenting code), distributed version control (e.g. git, mercurial), issue tracking system (e.g. Jira), and CI/CD tools (Travis, Jenkins)
Experience with at least two of the following: workflow/pipeline frameworks (Luigi, Airflow, etc), cloud computing & storage, software containerization, or Electronic Lab Notebooks
Nice to have:
Experience with at least one of: microbial or mammalian biology, translational research, clinical drug development
Broad understanding of proteomics tools used for visualization and analysis, including major proteomics search engines (e.g. MASCOT, Maxquant, ProteomeDiscoverer, Byonic, Progenesis QI) and protein ID and quantification algorithms/tools (Percolator, XCorr, ProteinProphet, PeptideProphet, MS-GF+)
Knowledge of statistics
Internal Number: 169
Calico is a research and development company whose mission is to harness advanced technologies to increase our understanding of the biology that controls lifespan. We will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Executing on this mission will require an unprecedented level of interdisciplinary effort and a long-term focus for which funding is already in place.