The Department of Systems Biology is seeking a systems biologist/bioinformaticist/computational biologist with extensive research experience for a Staff Associate position. The candidate filling the role will be using the algorithms developed in the Califano Lab to elucidate master regulators involved in tumorigenesis.
The Califano Lab focuses on the assembly and interrogation of gene regulatory models for the elucidation of mechanisms presiding over cell physiology and their dysregulation in disease, with specific applications to cancer, stem cells, and neurodegenerative disease. The lab, which integrates both experimental and computational research, has pioneered the first genome-wide regulatory model of human cells and a variety of methods for the identification of master regulators of aberrant transformation and physiological differentiation/maturation events and their controlling genetic alterations. These approaches have led to the discovery of several new genes in glioma, leukemia, lymphoma, and prostate cancer that can be targeted pharmacologically to abrogate tumorigenesis.
Internal Number: 5019
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