Drs. Brett Morrison and Jeffrey Rothstein at Johns Hopkins University have an immediate opening for a Post-Doctoral Research Fellow position investigating the role of immuno-metabolism in peripheral nerve regeneration and peripheral neuropathies. Our laboratory uses cell culture and animal models to study the mechanisms of nerve injury and develop new treatments that enhance the recovery from nerve injuries and peripheral neuropathies. Our laboratory is in a collaborative environment and shares space with other outstanding neuromuscular faculty, including Drs. Ahmet Hoke, Charlotte Sumner, Mohamed Farah, and Nicholas Maragakis. Specific areas of active research in the laboratory include:
Nerve regeneration following deletion or upregulation of the lactate transporter, monocarboxylate transporter 1 (MCT1), from macrophages in the peripheral nerve;
Impact of manipulating MCT1 in macrophages, Schwann cells, and neurons in models of experimentally-induced diabetic peripheral neuropathy and chemotherapy-induced neuropathy;
Manipulation of macrophage metabolism, by genetic and pharmacologic techniques, to develop new treatments for nerve regeneration and peripheral neuropathy
We are looking for highly motivated Ph.D. or equivalent scientists interested in advancing their career by working with other researchers at Johns Hopkins to investigate the intersection of immuno-metabolism and peripheral nerve diseases. Applicants should have experience in molecular biology, immunohistochemistry, and microscopy. The ideal applicant also has experience with animals, cell culture, and a background in neuroscience, immunology, or metabolism.
Internal Number: JHU122020
About The Johns Hopkins University
My laboratory in the Department of Neurology at The Johns Hopkins University School of Medicine in Baltimore Maryland investigates the mechanisms of nerve regeneration and common peripheral neuropathies. I have a particular interest in the contribution of cellular metabolism of immune cells to peripheral nerve diseases and use mouse models and cell cultures to investigate the pathogenesis of, and ultimately devise new treatments for, these diseases.