The Computational Cancer Biology Laboratory (azizilab.com) at Columbia University is seeking a passionate and self-driven ( grant funded, one - year) senior research technician with a background in molecular biology, cell culture, biochemistry or bioengineering, and wet-lab experience, to start in Jan 2020 or after, and work on ongoing research projects and assist with lab management responsibilities.
The lab research aims to address impactful questions around characterizing heterogeneity in the tumor microenvironment and underlying mechanisms of response to immunotherapies. Towards this goal, the wet lab works on single-cell (transcriptomic, epigenetic, TCR, etc) profiling of patient samples from different cancer types. The experimental lab closely interacts with the computational component of the lab in an exciting interdisciplinary environment with members from diverse backgrounds and skill sets.
The lab is affiliated with the Biomedical Engineering Department, the Irving Institute for Cancer Dynamics at Columbia University, and the Herbert Irving Comprehensive Cancer Center. The wet lab is located in the Columbia University Irving Medical Center (CUIMC) campus.
The successful candidate will be organized, maintain a clear, organized, up to date notebook and interact well with their supervisor and others in the laboratory.
(95%) Work on ongoing research projects and assist with lab management responsibilities, as directed by the Lab Director / PI. Collaborate with other labs / PI's under the direction of the Lab Director / PI.
(5%) Perform other duties and responsibilities, as directed by the Lab Director / PI.
Bachelor's with 3+ years of wet-lab experience
Skills and Knowledge:
Experience with molecular biology and genetic engineering techniques, high-throughput sequencing library preparation, mammalian tissue culture, and FACS
Highly responsible, independent and interested in working with a multidisciplinary team and interacting with clinical trial teams
Knowledge of policies and protocols related to functioning of a research lab incl. lab safety
Master's degree with three years of wet-lab experience
Financial literacy and experience or ability to manage lab inventory and supplies preferred
Interest in adapting or developing new single-cell technologies for cancer research would be a plus
Previous experience with single-cell genomic technologies would be preferable
Equal Opportunity Employer / Disability / Veteran
Columbia University is committed to the hiring of qualified local residents.
Internal Number: 505512
About Columbia University
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.