A post-doctoral research associate position is available starting as soon as possible to study programmed DNA elimination in multiple cellular organisms. Research will be conducted in the Wang lab that is located in the Ken and Blaire Mossman Building on the campus of the University of Tennessee, Knoxville.
Programmed DNA elimination is a developmental process in which portions of the genome are reproducibly eliminated. This process occurs in the single-cell ciliates as well as in diverse eukaryotes including nematodes and copepods. During DNA elimination in nematodes, the chromosomes break, regions are lost, and new chromosomes are formed. Areas under investigation in both nematode and copepod systems in the lab include 1) how break regions are identified and the mechanism of chromosome breaks, 2) how genome regions are marked for retention or elimination, 3) how eliminated chromosome regions are selectively lost, and 4) the contributions of epigenetic factors including histone modifications, 3D genome organization, and non-coding RNAs to DNA elimination.
Candidate is expected to design and carry out independent research, write fellowship applications (if applicable), and publish papers. Candidate must be self-motivated, has a strong aptitude for research, and the ability to quickly learn new areas of research and carry out experiments in a new system. The candidate's primary responsibility will be to conduct independent experiments. Good organizational and computer skills and the ability to work independently as well as part of a research team are necessary.
Successful candidate is expected to be a curious, highly motivated individual, with a positive attitude, and strong interpersonal skills. Candidate is also expected to direct independent projects, assist in mentoring junior lab members, and apply for independent fellowship funding.
Internal Number: 191911
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