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The Gerner Lab in the Department of Immunology at the UW School of Medicine has an excellent opportunity for a Research Scientist 2 (RS2).
Research in the Gerner lab investigates the development of immune responses to vaccination, infection with Mycobacterium tuberculosis, or during cancer development using mouse models. The lab uses various advanced microscopy techniques, such as multi-parameter confocal imaging and intravital 2-photon microscopy to investigate these processes directly in vivo. Together with other lab members, the RS2 will work on various aspects of the imaging pipeline to investigate how cellular positioning in tissues influences immune responses in diverse immunological settings. The RS2 will also work on implementing new imaging and staining approaches to better characterize different analytes of interest. Additional opportunities lie in development of image informatics tools to better understand complex patterns of cellular positioning. Together, this will advance biomedical technology development and promote a better understanding of immune response in diverse inflammatory settings directly in vivo.
Perform various aspects of tissue preparation and confocal imaging (organ isolation, tissue sectioning, staining, confocal imaging).
Panel testing and development (test and validate various antibody staining panels, as well as test different fluorophores for confocal imaging).
Integrate published methods for highly multiplexed imaging and in situ analysis of gene expression.
Use established computational pipelines to analyze image data.
Use statistical approaches to perform sample analysis
Help other lab members with experiments related to the central project
Data Analysis/Reporting, Data Presentation, and Scientific Manuscript Writing:
Incumbent will regularly present their findings in lab meetings and assist with preparation of presentations for professional conferences.
Incumbent will also assist lab members with publishing findings for peer-reviewed journals.
LEAD/SUPERVISORY RESPONSIBILITIES The RS2 will receive instruction on specific project objectives and responsibilities and will have regular oversight from the PI as well as other team members. The RS2 may also help train and monitor the work of junior staff using the developed tools and will interact in a collaborative manner with other teams to accomplish overarching goals.
Bachelor’s in Molecular Cellular Biology, Immunology, Cancer Biology, Microbiology, Bioinformatics, Biotechnology, or related field.
At least two years of relevant experience, ideally with histology, microscopy, or bioinformatics. Relevant experience gained while in graduate school is acceptable.
Master’s degree or higher in Molecular Cellular Biology, Immunology, Cancer Biology, Microbiology, Bioinformatics, Biotechnology, or related field.
CONDITIONS OF EMPLOYMENT The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
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