FORMA Therapeutics, Inc. (Watertown, MA) is a patient-focused, Cambridge-area, private biotechnology corporation dedicated to the discovery and advancement of life-saving therapies to patients across multiple therapeutic areas. While advancing multiple novel small molecule therapies discovered at FORMA in ongoing Phase I and Phase II clinical trials for diverse indications in oncology, hepatology and hematology, FORMA remains committed to the cutting-edge discovery of novel chemical matter for clinically relevant disease targets.
We are seeking a passionate laboratory scientist with the experience to design, implement and run both biochemical and cellular assays. This position is a key leadership role in the Lead Discovery and Optimization Group, which is a pivotal team responsible for assay development, High Throughput Screening, DNA-Encoded library selections & hits-to-leads support for FORMA’s diverse pipeline. The ideal candidate will be able to help evolve FORMA’s hit identification and hits-to-lead endeavors through embracing novel assay technologies, enhancing overall process and actively drive internal and external partnerships.
Excellent scientific depth with a strong understanding of all facets of automation and technology
Solid organizational skills applied to defining and optimizing workflows for maximum efficiency
Consistently demonstrates teamwork skills and has experience coaching and mentoring others
Strong ability to evaluate processes and drive the implementation of effective change
Excellent cross-functional collaboration, communication, and interpersonal skills
Highly self-motivated and able to work efficiently and productively in a rapidly-growing fast-paced company
Ph.D. or Masters Degree in Biochemistry and/or Cell Biology with industry experience
Demonstrated experience in Assay Development, Automation, Biochemistry, Cell Biology
Strong leadership in the Lead Discovery and Optimization group, responsible for assay design, high-throughput screening (HTS), and hit-to-lead program support
Hands-on execution of mechanistic assays (e.g. Determination of Ki, Kd, drug residence times, slow/irreversible binding and mode of inhibition from catalytic and binding studies)
Experience with high throughput data management, data flow, analysis and visualization (e.g. ABase, Genedata, Spotfire, Vortex)
Familiarity with robotic automation
Responsible for establishing, monitoring and maintaining a stable and productive environment through Quality Control, preventative maintenance and standard operating procedures
Responsible for setting and maintaining the highest scientific standards, developing skill-based competence, providing flexible project support as well as coaching and mentoring team members to maximize their potential
Demonstrated ability to collaborate with cross-functional teams in Medicinal Chemistry and Biology
Extensive hands-on experience in biochemical and/or cellular assays (384 or 1536 plate format), associated assay technologies and instrumentation for drug discovery is a must
Internal Number: 11179
About FORMA Therapeutics
FORMA Therapeutics is focused on the discovery, development and commercialization of transformative medicines that will make a difference for patients in need. A fully-integrated biopharmaceutical company, FORMA’s validated, proprietary R&D engine combines deep biology insight, chemistry expertise and clinical development capabilities to create differentiated drug candidates with best-in-class or first-in-class potential. FORMA has delivered high-value clinical candidates to its partners and generated a broad proprietary portfolio of programs, ranging from pivotal to preclinical-stage, with the potential to provide profound patient benefit in hematology, oncology, and metabolism indications.
FORMA is headquartered in Watertown, MA near the epicenter of the Cambridge Life Sciences cluster, with additional chemistry operations in Branford, CT. Check us out at www.formatherapeutics.com.