Are you passionate about collaborating with a team of clinicians and scientists at Memorial Sloan Kettering Cancer Center?
Then join us here at MSK, where we can provide you with the opportunity to make a difference with your career. The Innovation Laboratory is searching for an outstanding Senior Computational Biologist with a strong interest in developing and applying bioinformatic/quantitative methods to problems in translational cancer biology. We believe that this is an exciting role for someone who has the right background to be apart of our dynamic team and who wants to apply their skills to support our mission here. The Innovation Laboratory within the CMO is a group of experimental and computational scientists dedicated to the creation and optimization of genomic assays for near-term clinical use. Active areas of research include:
Ultra-deep sequencing of circulating cell-free DNA from plasma and other bodily fluids
Optimization of DNA and RNA capture techniques
Molecular profiling of challenging clinical samples (FFPE tissue, small biopsies, cytological specimens)
Integration of somatic and germline genomics
Novel biomarker discovery
Single-cell genomics applications
The goals of the Innovation Laboratory are:
Develop and validate genomic assays and associated computational pipelines for the molecular characterization of human tumors,
Evaluate new technologies for potential clinical utility,
Pilot new technologies in collaboration with clinical and translational investigators, and 4) to work with clinical laboratories to ensure quality standards mandated by CLIA. New clinical assays will be deployed both retrospectively to discover biomarkers that track with therapeutic response, and prospectively to inform treatment decisions and guide patients to promising clinical trials.
A skilled mentor who will serve as a subgroup team lead for Innovation bioinformatics
Capable of building strong collaborative relationships and working with others to meet shared objectives and goals
A good decision-maker, with proven success at making timely decisions that keep your own work and that of your team moving forward
Effective at working when presented with complex, and sometimes contradictory, information
An effective communicator, capable of determining how best to reach different audiences and executing communications based on that understanding
Work in concert with the group leader and the Innovation team to provide support to research projects at the Center
Design, develop, and implement software tools for processing and analyzing high-throughput next-generation sequencing data
Provide one-on-one consultation and training to research scientists, bioinformatics scientists, and software engineers at the Center in the use of bioinformatics software tools and databases
Be responsible for conducting independent analysis and interpretation of genomic and other multi-omic data generated by the group
Help facilitate collaborations and research opportunities with scientists and clinicians at MSK
Masters degree with 4-7 years of experience in biological science, physics, applied mathematics, computer science, bioinformatics, or a related field. PhD degree with 2-4 years of experience is preferred.
Solid programming skills and proficiency with scientific computing software (Matlab, R) and scripting languages a thorough understanding and experience in statistics is strongly preferred
Experience in statistical genetics/genomics and a familiarity with next-generation sequence data and analysis tools extensive research experience in the biological sciences is strongly preferred
To be able to work both independently and collaboratively and make necessary connections with experts in various biological and clinical groups
To be highly motivated with excellent oral and written English communication skills experience in delivering oral scientific presentations and writing scientific articles is strongly preferred
Internal Number: 2019-37842
About Memorial Sloan-Kettering Cancer Center
As one of the world's premier cancer centers, Memorial Sloan-Kettering Cancer Center is committed to exceptional patient care, leading-edge research, and superb educational programs. The close collaboration between our physicians and scientists is one of our unique strengths, enabling us to provide patients with the best care available today as we work to discover more effective strategies to prevent, control, and ultimately cure cancer in the future. Our education programs train future physicians and scientists, and the knowledge and experience they gain at Memorial Sloan-Kettering has an impact on cancer treatment and the biomedical research agenda around the world.