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Post Doc Instructions:
Please do not submit an application to this posting.� To apply for this postdoctoral research opportunity, follow the directions below in �Applicant Special Instructions�.
We are seeking a highly-motivated postdoctoral research associate to join the Singh Lab in our effort to identify the mechanisms underlying failure of adoptive cellular immunotherapies. The Singh Lab studies how chimeric antigen receptors (CARs) direct functional and dysfunctional T cell biology in the treatment of cancer. We are specifically interested in elucidating how interactions between CAR T cells and cancers result in the initiation and maintenance of biological pathways that drive T cell dysfunction. Our overall goal is to translate these discoveries using cutting-edge cellular engineering platforms to design improved, more effective cell therapies for cancer.
Through this postdoctoral experience, the researcher will have the opportunity gain or further develop expertise in immune cell signaling, proteomics, and single cell profiling of transcription and epigenetic regulation in both in vitro models and primary samples.
In addition to close mentorship by the PI, high-quality research facilities and a supportive and collaborative scientific research community, there is ample career and professional development training provided through several on-campus resources, including the Office of Postdoctoral Affairs, Career Center and Teaching Center. More information can be found at postdoc.wustl.edu/prospective-postdocs.
The postdoctoral research associate will train under the supervision of Dr. Nathan Singh, Assistant Professor of Medicine in the Division of Oncology.
Duties will include:
Independently manages the research projects, which should lead to first author publications.
Develops expertise in engineered T cell biology, genome engineering, transcriptomics and epigenomics.
Develops expertise in scientific writing, public speaking, networking and critical evaluation of scientific literature.
Presents work both inside and outside of the University.
Assists with grant preparation and reporting.
Prepares original manuscripts.
Designs research experiments.
Evaluates research findings and develops troubleshooting approaches.
Maintains ethical standards of research.
Documents efficiently and thoroughly in an electronic notebook.
Engages in open and timely discussion with his/her mentor regarding possession or distribution of material, reagents, or records belonging to their laboratory and any proposed disclosure of findings or techniques privately or in publications.
Demonstrates and maintains a respectful workplace environment with collegial conduct towards co-trainees, staff members and members of the research group.
Adheres to all applicable University policies, procedures and regulations.
Department Name/Job Location:
This position is in the Department of Internal Medicine, Division of Oncology. This position is for the Medical School Campus.
Ph.D., M.D. or an equivalent terminal doctoral degree.
Experience in human immunology, genome engineering and molecular biology.
Background in informatics analysis.
Base pay commensurate with experience.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Interested applications should send their CV, contact information for three references, and a cover letter outlining their previous work and future interests to firstname.lastname@example.org.
This position works in a laboratory environment with potential exposure to biological, chemical and radioactive hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.
Internal Applicant Instruction:
Please attach a copy of your most current signed performance evaluation (completed within the last 18 months) to your online account. If you have not received a performance evaluation, you may provide two current signed letters of recommendation (written within the last 18 months), preferably to include one letter from either a current or recent former supervisor. To attach these documents, go to: My Career Tools, Add Attachment, Attachment Type – Performance Reviews or Letters of Recommendation.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.