The Department of Pathology and Laboratory Medicine at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for a Research Associate position in the Academic Support Staff. This appointment will be initially for one (1) year and continuation during that time period and renewal are based on satisfactory performance and availability of funding (limited to three (3) years). Expertise is required in the specific area of molecular biology, including but not limited to molecular virology, gene editing, and endogenous and chimeric gene expression, flow cytometry and analysis, aseptic tissue culturing, bioinformatics, and in vivo xenograft assays to test the efficacy of new chimeric antigen receptor T cell products. The successful candidate will have proven competency in developing new chimeric antigen receptor T cell products and conducting in vitro studies and in vivo xenograft assays to evaluate their efficacy. Importantly, this position requires the demonstrated ability to train and manage research staff, and work collaboratively within CCI and other departments. Applicants must have an M.D. or Ph.D. or M.D./Ph.D. degree.

Responsibilities may include independently designing and performing animal experiments using primary human cancer tissue, cancer cell lines and primary human T cells; independently designing and performing in vitro experiments with human T cells using techniques that include but are not limited to flow cytometry, ELISA and cytotoxicity assays; training and managing technical staff in the performance of in vitro and animal research experiments under the guidance of the principle investigator; maintaining accurate logs and laboratory reports and supervise when appropriate staff logs; attending and participating in laboratory meetings and national scientific conferences; drafting reports and manuscripts summarizing research results.

The successful applicant will have an opportunity to develop and direct research projects in cellular immunotherapy, be involved with research into adoptive T-cell immunotherapy, and manage a collaborative research project under the guidance of the principle investigator.

We seek candidates who embrace and reflect diversity in the broadest sense. The University of Pennsylvania is an EOE. Minorities/women/individuals with disabilities/protected veterans are encouraged to apply.