Job Description A Researcher 5 position is available in the laboratory of Dr. Stefani Thomas in the Department of Laboratory Medicine and Pathology at the University of Minnesota. The Thomas lab is part of the Masonic Cancer Center, University of Minnesota – a comprehensive cancer center designated by the National Cancer Institute. The research in Dr. Thomas’s lab focuses on deploying mass spectrometry techniques to delineate the proteome-level predictors of improved response to targeted therapy for the treatment of ovarian cancer. We are specifically working towards a long-term goal of developing and validating biomarkers that will enable the optimal stratification of ovarian cancer patients for personalized treatment modalities yielding increased survival. Particular emphasis is placed on elucidating the proteomic determinants of PARP inhibitor treatment response in the context of homologous recombination deficiency. Highly motivated individuals with a strong background in analytical chemistry, biochemistry or molecular and cellular biology are encouraged to apply. The ideal applicant will have experience in mass spectrometry-based quantitative proteomics as evidenced by authorship on peer-reviewed publications. The ability to work effectively with a cross-disciplinary team of scientists is required due to the highly collaborative nature of the research in the laboratory.
Responsibilities • Participate in the design, planning and execution of experiments towards the accomplishment of the goals set forth in various research projects • Maintain awareness of latest advances in related fields of research • Implement and/or develop standardized protocols • Analyze and interpret experimental results • Contribute to manuscript preparation • Operate LC-MS instrumentation and interact with personnel in mass spectrometry core facilities and the Advanced Research and Diagnostic Laboratory (ARDL) at the University of Minnesota • Conduct laboratory management-associated tasks including, but not limited to, placing orders, maintaining reagent and supply inventory, maintaining and troubleshooting general laboratory equipment, and ensuring compliance with safety regulations
The University of Minnesota offers a comprehensive benefits package including: • Competitive wages, paid holidays, vacation and sick leave • Low cost medical, dental, and pharmacy plans • Health care and dependent daycare flexible spending accounts • Excellent retirement plans with employer match • Disability and employer paid life insurance • Wellbeing program with reduced insurance premiums • Tuition reimbursement opportunities covering 75%-100% of eligible tuition • Student loan forgiveness opportunity • Opportunities for growth and promotion • Employee Assistance Program For more information regarding benefits: https://humanresources.umn.edu/sites/humanresources.umn.edu/files/2019_tcd-fpa-75100-ben-0105-10_0.pdf
Required • Master’s degree in a Biology- or Chemistry-related field and 1 year of related research experience • Hands-on experience with operating and troubleshooting LC-MS systems • Experience in mammalian cell culture, molecular and cellular biology techniques, and sample preparation for mass spectrometry-based proteomics • Willingness to learn new techniques and methods • Proficiency with Microsoft Office • Excellent analytical, critical thinking, communication and inter-personal skills • Strong work ethic, attention to detail and excellent organizational skills
Preferred • Experience with various software programs used to process and analyze mass spectrometry data • Familiarity with developing and validating novel assays for clinical diagnostics
Internal Number: 333552
About University of Minnesota, Twin Cities
The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.