This Researcher 2 position is in the Herschhorn Lab in the Division of Infectious Diseases and International Medicine, Department of Medicine at the University of Minnesota. We are a new and energetic research group that works on exciting directions to understand and target HIV-1 host interactions at the molecular and cellular levels. We use interdisciplinary approaches at the interface of synthetic and molecular virology, immunology and cell biology to gain new insights into complex biological processes with the aim of translating these insights into novel therapies and vaccines to treat and prevent viral infections.
Job Duties/Responsibilities 80% - Research Duties include, but not limited to, the preparation of viral immunogens, immunization of animals used as model system, bleeding animal and testing antibody response using ELISA and viral assays. Training and expected work will include work with animals, measurements of viral entry, expression of proteins in animal cells, purification of recombinant proteins, and ELISA. Critical analysis of published studies, data analysis and integration, interpretation of the experimental results, troubleshooting and developing new hypotheses based on current results, and designing research projects. Keep an updated lab notebook, maintain lab equipment as needed, write and update required protocols, participate in lab meeting, coordinate work with scientific collaborators.
20% - Administration Duties include, but not limited to, animal ordering, maintaining all records related to animal-work training, interacting with the animal facility technicians and veterinarians, complying with all institutional regulations, complete routine tasks for lab maintenance. Writing and revising institutional IACUC protocols, preparation of figures, presentations and manuscripts for publication. Other administrative tasks as assigned
Required Qualifications: (Must be documented in application materials or resume)
BS/BA and 1 years of related experience of a combination of education and work experience to equal five years
Experience with Animal Models (i.e. mouse, rat, guinea pig, rabbit)
Excellent Communication and Organization Skills
Proficiency in Microsoft Office (Word, Excel, PowerPoint)
Ability to Work Independently and Team, Solve Problems, Work Under Pressure, Multi-Task
Willingness to Work with Bacteria, Bacteriophages, Human Cells/Tissues and Defective HIV-1 in a BL2+ Facility
Experience in Immunological Methods, such as ELISA, Antibody Characterization, Western Blot
Demonstrated Experience with Tissue Culture Techniques
Previous Experience Working in Bench Research Laboratory Setting
Advanced Degree or Additional Experience
Formal Education in Veterinary or Pre-Veterinary Sciences
Experience Writing, Following, and Using IACUC Protocols
Experience with Protein Purification
Experience with Animal Immunizations
Experience with Virus-Like Particles Production/Concentration
Advanced Experience in Molecular Biology Methods (i.e. Cloning and PCR, Transfection, Isolation of Peripheral Blood Mononuclear Cells (PBMC) from Blood, and Viral Assays)
Exceptional Organizational skills and Attention to Detail for Laboratory and Administrative Tasks, such as Lab Ordering and Compliance
Internal Number: 333540
About University of Minnesota, Twin Cities
The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.