The Wyss Institute seeks a talented energetic professional to join our community as a Staff Scientist in the field of Tissue and Organ Regeneration. This entrepreneurially minded individual will work closely with Wyss Faculty and act as an intellectual 'bridge' scientist, who will bring both tissue engineering bench expertise and industry / startup experience in product development to the table, and combine these strengths to drive basic science findings from your future colleagues at Harvard, MIT, and Boston University into pre-clinical animal models, and eventually to patients.
The Staff Scientist will lead and participate in ongoing initiatives towards the goal of whole organ bioengineering at the Wyss Institute. With strong technical guidance from leaders in the field of 3D Organ Engineering, the Staff Scientist will develop and perform a broad range of research activities and procedures demonstrating speed, precision, and an excellent understanding of the theory behind these techniques and collaborate closely with junior postdocs and staff members of the team.
This position is an exciting opportunity to combine cutting edge hands-on research with the strategic considerations of technology translation and product development. The Staff Scientist will work closely with colleagues in related functions at the Wyss Institute and the Office of Technology Development at Harvard University. Responsibilities include:
Assist in the development of large-scale organ-specific tissues, while working with a multi-disciplinary team that includes technical, clinical, and development collaborators.
Design, engineer, and iterate organ-specific constructs based on insights gleaned from collaborating team members who are focused on identifying cell-cell, cell-matrix, and soluble/circulating factors that influence tissue growth and function, with the aim of producing translationally-relevant model systems that enable pre-clinical testing.
Contribute to the isolation and/or maintenance of primary and/or stem cell-derived cell populations. Candidate must have experience with mammalian cell culture and aseptic technique.
Design and conduct implantation experiments in appropriate animal models.
Monitor and analyze organ-specific tissues during in vitro and in vivo expansion, including preparation and handling, collection and analysis of pre- and post-expanded cell populations/tissues, and functional assessment of tissue output.
Manage scientific and technical activities across this effort, including interactions with the involved labs based at Harvard, MIT, and BU and their researchers and trainees. Develop experimental plans and successfully execute research timelines to meet translation goals and milestones, both independently and as a daily manager of a small team.
Provide in-depth expertise and hands-on experience in developing functional assays. Implement quantitative in vitro assays for evaluating tissue functionality, stability, and safety.
Develop and standardize organ-specific tissue manufacturing and surgical protocols for in vivo studies in small and large animals.
Participate in writing research proposals, reports, patent applications, presentations and publications, providing critical data, figures or information for grant and patent submissions.
The mission of the Wyss Institute for Biologically Inspired Engineering at Harvard University is to transform human healthcare and the environment by emulating the way nature builds. Developed as an alliance between Harvard and other premier academic and clinical partner institutions, Institute faculty and staff collaborate in high-risk, fundamental research and science-driven technology development. A major focus of the Institute is to translate the technologies developed by its faculty and staff into commercial products and therapies through collaborations with clinical investigators and establishment of corporate alliances and launching startup companies. For more information, visit: http://wyss.harvard.edu/.
Harvard offers an outstanding benefits package including:
Time Off: 3 - 4 weeks paid vacation, paid holiday break, 12 paid sick days, 11.5 paid holidays, and 3 paid personal days per year.
Medical/Dental/Vision: We offer a variety of excellent medical plans, dental & vision plans, all coverage begins as of your start date.
Retirement: University-funded retirement plan contributions from 5% to 15% of eligible compensation, based on age and earnings with full vesting after 3 years of service.
Tuition Assistance Program: Competitive tuition assistance program, $40 per class at the Harvard Extension School and discounted options through participating Harvard grad schools.
Transportation: Harvard offers a 50% discounted MBTA pass as well as additional options to assist employees in their daily commute.
Wellness options: Harvard offers programs and classes at little or no cost, including stress management, massages, nutrition, meditation and complimentary health services.
Harvard access to athletic facilities, libraries, campus events and many discounts throughout metro Boston.
Salary Grade: 058
Union: 00 - Non Union, Exempt or Temporary
Advanced degree in a biological science, bioengineering, or related discipline, with a strong understanding of cell biology, physiology, and/or tissue engineering.
A minimum of 7 years of related experience.
Ph.D. in biological science, bioengineering or related discipline strongly preferred.
Demonstrates a broad theoretical and practical knowledge within the fields of biofabrication, tissue engineering, and cell biology.
Exhibits a good understanding of technology translation and product development with the ultimate goal of product commercialization.
Strong scientific track record demonstrating well-organized design and execution of studies.
Extensive experience with in vivo and in vitro tissue engineering, characterization, and implantation.
Demonstrated success in leading and working in cross-functional teams.
Comfortable in a fast-paced translational environment and able to adjust workload based upon changing priorities.
Flexible and cooperative sprit with strong commitment to collaboration and team efforts.
Strong oral and written communication skills, with a habit of paying significant attention to detail.
EQUAL OPPORTUNITY EMPLOYER: We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.
Internal Number: 50647BR
About Harvard University Medical School
Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders in many disciplines who make a difference globally. The University, which is based in Cambridge and Boston, Massachusetts, has an enrollment of over 20,000 degree candidates, including undergraduate, graduate, and professional students. Harvard has more than 360,000 alumni around the world. The University has twelve degree-granting Schools in addition to the Radcliffe Institute for Advanced Study, offering a truly global education. Established in 1636, Harvard is the oldest institution of higher education in the United States.