The Longden Lab is seeking a highly motivated, independent and creative postdoctoral researcher to join our team.
Our research uses advanced imaging techniques to understand neurovascular interactions in health and disease, with a particular focus on the physiological contributions of vascular ion channels and GPCRs to the control of blood flow to support brain metabolism. We are interested in determining how this control is disrupted in dementia, and we are developing novel approaches to correct blood flow deficits in this context to protect the brain and/or rescue neuronal function.
Techniques in use in the lab include in vivo multiphoton microscopy to measure calcium signaling and blood flow in the brains of anesthetized or awake animals, and miniscope imaging in freely behaving animals. The lab also has strengths in patch clamp electrophysiology on cells of the neurovascular unit, optogenetics, DREADDs, and pressure myography on isolated brain microvessels.
Physiologists at the University of Maryland School of Medicine integrate molecular, cellular and systems biology. Our department has especially strong traditions in neuroscience, cardiovascular-renal biology, and reproductive biology. The University is located in Baltimore adjacent to Oriole Park at Camden Yards and the Raven’s M&T Bank Stadium and within walking distance of the first-rate restaurants, shopping, and entertainment at Baltimore's Inner Harbor. The areas of Mt Vernon, Federal Hill, Fells Point, Canton, and Harbor East are vibrant, rapidly growing communities with excellent residential options. Nationally ranked schools from kindergarten through high school are found in Baltimore's many private academies and the surrounding county public school systems.
Interested applicants should send their CV and two references to:
The ideal candidate will have a PhD in physiology, pharmacology, neuroscience or a related discipline. Prior experience in one or more of the approaches described above is preferred but not essential. More important is dedication to and passion for cutting-edge research. Preferred start date is January 2020 but this can be negotiated.
Additional Salary Information: Salary is determined according to the recommendations of the NIH pay-scale, an excellent benefits package is also provided.
Internal Number: 01
About Longden Lab
The Longden Lab is located in Howard Hall in the University of Maryland School of Medicine.
Physiologists at the University of Maryland School of Medicine integrate molecular, cellular and systems biology to discover how life works. Our department has especially strong traditions in cardiovascular-renal biology, neuroscience and reproductive biology.
Our graduate students, post- doctoral fellows and faculty are working to unravel mysteries in signaling in heart and vascular smooth muscle, muscle contraction, cancer metastasis, hormone action, learning and memory, salt and water balance, and synaptic transmission.
We are helping to uncover the causes and mechanisms of human disease, including Alzheimer's, cancer, heart failure, hypertension, muscular dystrophy, and depression. We invite you to join us and make exploration and discovery your life's work.