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Application Review Date
The First Review Date for this job is: August 20, 2019
Tuberculosis has been a major global health concern for well over a century. Although many potential treatments have been vigorously pursued, conventional strategies have failed to eradicate TB infection and, in fact, the global threat has grown over the last couple decades, potentially stemming from the fact that treatment attempts have neglected to take into account the deeply integrated, symbiotic-like relationship between Mycobacterium tuberculosis and its host that has developed over 40,000 years of human/bacterial co-evolution.
The Cox Lab (housed in the UC Berkeley MCB Department) aims to understand the key mechanisms that dictate the M. tuberculosis-human relationship with the goal of breaking these ties, targeting either host or pathogen factors to eliminate M. tuberculosis infection and use that knowledge to contribute to solving a steadily increasing threat in global health.
Assist and perform research experiments using Molecular/cell biology and computational approaches: DNA cloning, qPCR, transfection, lentivirus production, CRISPR genetics, next-generation sequencing, genomics, transcriptomics.
Learn and carry out biochemical techniques such as SDS-PAGE, affinity purification, western blotting.
Assist and carry out molecular genetic methods to overexpress and silence gene expression in mammalian cell culture, molecular cloning techniques and mutagenesis, cell biological assays to assess protein function and localization, western blotting, quantitative PCR analysis, and other assays that are critical for advancing our studies of infectious diseases.
Present in lab meetings of research accomplishments, and participate in manuscript and grant writing.
Supervising undergraduate student assistants to ensure successful completion of fundamental tasks, including ordering/stocking laboratory supplies, preparation of lab stocks, mouse breeding, and general laboratory maintenance.
Assist with on-boarding of new lab personnel, including key car access and safety training
Coordinating vendors in procurement and maintenance of lab equipment
Perform other duties as assigned Required Qualifications
Demonstrated experience with molecular cloning and culturing of bacteria and/or mammalian cells
Facility with computer programming and/or working with large data sets
Familiarity with DNA software
Ability to independently make solutions based on molarity and % composition Preferred Qualifications
Demonstrated knowledge of computer programming languages (e.g. Python, R, bash).
Demonstrated knowledge of command line experience in Linux and Python
Manipulation of mammalian cells by transfection or viral transduction Salary & Benefits
This position is a non-exempt, bi-weekly paid position. Hourly pay for this role is commensurate with experience.
Please submit your cover letter and resume as a single attachment when applying.
Conviction History Background
This is a designated position requiring fingerprinting and a background check due to the nature of the job responsibilities. Berkeley does hire people with conviction histories and reviews information received in the context of the job responsibilities. The University reserves the right to make employment contingent upon successful completion of the background check.
The University of California was chartered in 1868 and its flagship campus - envisioned as a "City of Learning" - was established at Berkeley, on San Francisco Bay. Today the world's premier public university and a wellspring of innovation, UC Berkeley occupies a 1,232 acre campus with a sylvan 178-acre central core. From this home its academic community makes key contributions to the economic and social well-being of the Bay Area, California, and the nation.