The Wyss Institute of Biologically Inspired Engineering at Harvard University is seeking a Research Assistant III to significantly contribute to a research program involving the use of microfluidic human lung in vitro models to the pathology of cystic fibrosis, and the contribution of infection within this model. The successful candidate will be a part of our Bioinspired Therapeutics and Diagnostics Platform and also work with our internal drug discovery team to leverage this knowledge to identify and develop novel anti-inflammatory therapies. They will be responsible for the optimization and execution of microfluidic Organ on Chip primary cell culture, bacterial infection, and the development and validation of various in-vitro cell based assays, including, but not limited to, bacterial and cell based qPCR/TaqMan, ELISA, westerns, enzymatic assays, imaging, and immune cell-based assays. Previous experience with mammalian cell culture is a must. The candidate will be expected to work independently under minimal supervision of staff and faculty to design experiments, learn new skills, troubleshoot, and to contribute intellectually to the project. Previous knowledge of lung epithelial and/or immune cell culture, as well as IPS technology, is a plus. In addition, the candidate is expected to order supplies, perform support activities and lab maintenance, and function in a team-oriented environment with other scientists and staff at the Institute. The candidate will participate in the preparation of manuscripts and patent applications. Under the supervision of staff, the candidate may present data and conclusions at meetings within the Wyss Institute.
This is a one-year term position with the possibility of renewal.
The mission of the Wyss Institute for Biologically Inspired Engineering at Harvard University is to transform human healthcare and the environment by emulating the way nature builds. Developed as an alliance between Harvard and other premier academic and clinical partner institutions, Institute faculty and staff collaborate in high-risk, fundamental research and science-driven technology development. A major focus of the Institute is to translate the technologies developed by its faculty and staff into commercial products and therapies through collaborations with clinical investigators and establishment of corporate alliances and launching startup companies. For more information, visit: http://wyss.harvard.edu/.
Harvard offers an outstanding benefits package including:
Time Off: 3 - 4 weeks paid vacation, paid holiday break, 12 paid sick days, 11.5 paid holidays, and 3 paid personal days per year.
Medical/Dental/Vision: We offer a variety of excellent medical plans, dental & vision plans, all coverage begins as of your start date.
Retirement: University-funded retirement plan contributions from 5% to 15% of eligible compensation, based on age and earnings with full vesting after 3 years of service.
Tuition Assistance Program: Competitive tuition assistance program, $40 per class at the Harvard Extension School and discounted options through participating Harvard grad schools.
Transportation: Harvard offers a 50% discounted MBTA pass as well as additional options to assist employees in their daily commute.
Wellness options: Harvard offers programs and classes at little or no cost, including stress management, massages, nutrition, meditation and complimentary health services.
Harvard access to athletic facilities, libraries, campus events and many discounts throughout metro Boston.
Salary Grade: 054
Union: 55 - Hvd Union Cler & Tech Workers
Bachelor's degree in cell biology or Bioengineering. At least two years of experience involving aseptic mammalian cell culture and molecular biology techniques, such as ELISA, PCR, microscopy or related experience. Advanced degree may count towards years of experience.
Advanced degree in Cell Biology or Bioengineering preferred. Candidates with experience in multiple primary cell types, specifically lung and immune, will be strongly considered. Experience with cell culture in microfluidic device is a plus. Ability to work well independently and to collaborate with a multidisciplinary group is essential. The candidate should be proficient with personal computers and applicable software packages (Microsoft Office). Good written and oral communication skills are essential. The candidate should be highly motivated, detail-oriented, organized, and able to take initiative.
EQUAL OPPORTUNITY EMPLOYER: We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.
Internal Number: 50520BR
About Harvard University Medical School
Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders in many disciplines who make a difference globally. The University, which is based in Cambridge and Boston, Massachusetts, has an enrollment of over 20,000 degree candidates, including undergraduate, graduate, and professional students. Harvard has more than 360,000 alumni around the world. The University has twelve degree-granting Schools in addition to the Radcliffe Institute for Advanced Study, offering a truly global education. Established in 1636, Harvard is the oldest institution of higher education in the United States.