Proficient research laboratory specialist with a sophisticated understanding of techniques and a solid foundation in the underlying science, gained from professional laboratory and research experience.
Under minimal supervision, performs research laboratory experiments by following established procedures and protocols. Participates in the design of experiments and analyzes data. Works independently and manages daily research projects. The senior research specialist will assist the principal investigator in the development and coordination of projects, experimentation, data collection/maintenance, and organization of the laboratory. Runs lab tests and completes measurements as assigned. Identifies and resolves problems and uses analytical and decision making skills to implement assigned projects. Produces and maintains meticulous laboratory notes/documentation and may contribute to result presentations and manuscripts.
Duties and Responsibilities
Performs research lab experiments to include: generation and analysis of mouse models of ALS, FTD and IBM; biochemical, pathological and behavioral assessment of delivery and efficacy of AAV gene therapy in mouse models of ALS, FTD and IBM; and development of fluid biomarkers for ALS, FTD, AD and IBM. Records and reports all laboratory activities, laboratory notes, and outcomes in a detailed and organized manner.
Performs as Lead, responsible for training and lab lead of tissue culture technicians and student workers.
Manages the daily operation of the Wong lab which includes working closely with investigators to assess their needs and develop protocols to meet their individual needs. Reviews papers and written protocols to facilitate Best Outcomes.
Monitors biohazard/radiation safety standards and proper handling of potentially hazardous chemical and biological agents and/or radiation sources in the workplace.
Responsible for routine operational activities such as; ordering supplies and materials, reviewing inventory, maintaining up to date records of tests, etc. Preventative maintenance of equipment. Monitors inventory levels and proper storage of materials and supplies in accordance with established policies and procedures.
Exchanges routine information in an appropriate manner requiring good oral and written communication.
Reports and records outcomes/results. Exchanges routine information in an appropriate manner requiring good oral and written communication. Regular interaction with students, vendors, post-doctoral fellows and faculty members.
Performs miscellaneous related duties as assigned.
Equipment, Machine, or Tool Requirements:
Computer and Laboratory equipment
Operates lab equipment such as: centrifuges and PCR machines
Bachelor’s degree in biological sciences, chemistry, or related field required.
Master's degree highly desired
4 years related research laboratory experience performing relevant or related techniques required.
Master's, with related graduate research, may substitute for experience to the extent permitted by the JHU equivalency formula.
Special Knowledge, Skills, or Abilities / Competencies:
Advanced knowledge of good lab practices.
Ability to handle and experimentally inject mice, collect samples and ear-notching etc.
Advanced organizational skills a must.
Excellent record keeping and documentation skills, required.
Ability to work independently, under minimal supervision.
Strong decision making skills and good judgment.
Work Environment /While performing the duties of this job:
Work will require physical work, including a lot of time standing, walking, bending and reaching.
While performing the duties of this job, the employee is required to stand and walk up to 85% of the time. Frequently required to traverse throughout the laboratory; to other work areas on campus. In some areas work space may be confined. The employee is required to operate computer keyboard, laboratory instruments, and small laboratory tools such as pipettes; as well as able to handle small animals.
Prolonged vision requirements including viewing computer screen, paper reports/documents, laboratory notes, charts and results.
Laboratory environment – Lab has biological hazards including infectious materials and radioactive materials. Assistance with regulatory compliance for animal, IBC and Radiation Safety will be required.
Exposure to toxins and infectious agents exist, but potential for personal injury or harm is minimized if established safety and health precautions are followed. Must refer to and are expected to comply with proper laboratory protocols and safety policy/procedures, and be familiar with material data safety sheets in assigned work areas. Working in laboratory where there may be discomforts due to odors, noise, temperature fluctuations, and working around lab equipment. Use of personal protective equipment may be advised or required.
Staff may be required to complete annual competency review, and must insure compliance with Johns Hopkins Policy, Laboratory Policy & Procedure, Health, Safety & Environment regulations, and all applicable privacy & confidentiality laws/practices.
Schedules will include expected weekend work and/or holiday assignment to check on mice. Required to report in the event of inclement weather or other emergency to check/care for mice.
Classified Title: Sr. Research Specialist Working Title: Sr. Research Specialist Role/Level/Range: ACRP/04/MC Starting Salary Range: $45,195-$62,225 (commensurate with experience) Employee group: Full Time Schedule: M-F 8:30 - 5:00 Exempt Status: Exempt Location: 04-MD:School of Medicine Campus Department name: 10003061-SOM Pat Neuropathology Personnel area: School of Medicine
The successful candidate(s) for this position will be subject to a pre-employment background check.
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During the Influenza ("the flu") season, as a condition of employment, The Johns Hopkins Institutions require all employees who provide ongoing services to patients or work in patient care or clinical care areas to have an annual influenza vaccination or possess an approved medical or religious exception. Failure to meet this requirement may result in termination of employment.
The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.
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