Chemical Capabilities & Screening (CC&S) is seeking a highly skilled individual(s) to fill the positions of (Associate) Principal Scientist and/or Senior Scientist, and join our team of experienced and accomplished colleagues.
Situated in the Affinity Screening & High Throughput Experimentation group within Screening & Compound Profiling (S&CP), the individual(s) will be responsible for developing an end-to-end workflow for the screening and analysis of DNA-encoded libraries (DEL's), and applying the approach to projects across the Merck pipeline as part of the Lead Discovery toolbox.
Required experience & skills:
Significant hands-on experience practicing DEL in a relevant field. Background in Molecular Biology & Protein Biochemistry.
Strong external record of scientific achievement (via. presentations, publications etc.).
Strong interpersonal, verbal and written communication skills.'
Preferred Experience & Skills:
Demonstrated expertise in DEL (including practice experience in the molecular biology of library generation, including an understanding of encoding/decoding Informatics).
Broad experience in Protein Biochemistry, especially around affinity immobilization and enrichment selection methods for soluble & membrane proteins.
Experience in the application of biochemical, biophysical and cell-based techniques to screen and/or assess pharmacologic MOA.
Previous experience in a Lead Discovery enterprise, with an appreciation for the interplay of complementary technologies.
Internal Number: DELT12
About Merck & Co.
Merck & Co., Inc., known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company-one that is ready to create a healthier future for all of us.
Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our blogal team, you'll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.